Best Greenville County Grants for Nonprofits in South Carolina

About PLTW Computer SciencePLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities enhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Computer Science program.
  • Example expansion activities include but are not limited to adding an additional PLTW Computer Science  course not previously offered,
  • and/or adding additional class periods of an existing PLTW Computer Science courses previously offered,
  • and/or training additional teachers in PLTW Computer Science courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $5,000
  • 2027-2028: $5,000

The Bank of America Charitable Foundation focuses on improving economic mobility and social progress through partnerships with nonprofits. It prioritizes basic needs, income creation, stable housing, and community empowerment. By supporting vulnerable populations, the foundation aims to enable individuals to achieve their goals and contribute positively to their communities. The foundation emphasizes sustainable progress, ensuring that all community members have access to essential resources and opportunities for growth.

About PLTW EngineeringPLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• Grantee must use their grant funds to expand their existing PLTW Engineering program.
  • Example expansion activities include but are not limited to adding an additional PLTW Engineering course not previously offered,
  • and/or adding additional class periods of an existing PLTW Engineering courses previously offered,
  • and/or training additional teachers in PLTW Engineering courses for the 2027-2028 academic year. 

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

The Hathaway Family Foundation Grant aims to enhance the lives of individuals in need within Greenville, South Carolina. This private foundation focuses on improving food security, access to quality healthcare, conservation efforts, and addressing homelessness. By supporting organizations that provide temporary shelters, mental health care, and food distribution, the foundation ensures targeted assistance for the most vulnerable populations. The foundation's commitment reflects a dedication to fostering community well-being and positive change.

About PLTW GatewayPLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine.3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunitiesEnhancing the quality of STEM teaching
• Providing professional development opportunities for students

Program Requirements:

• The purpose of this grant is to assist the grantee's implementation of the PLTW Gateway program.
• Grantee must offer at least one PLTW Gateway unit in the 2027-2028 academic year.
• Grantee may implement any PLTW Gateway unit of their choosing.

Grant Award and Distribution Schedule:

• Total Award: $10,000
  • 2027-2028: $10,000

The TD Bank Community Sponsorships Program, supported by the TD Charitable Foundation, provides funding for events and activities that positively impact communities from Maine to Florida. This initiative aims to enhance community awareness and foster partnerships among diverse groups, promoting economic development, cultural enrichment, and social responsibility. Organizations can apply for funding to support community-oriented programs, with applications reviewed quarterly. It's essential to submit applications at least 90 days before the event deadlines.

The CFG Capacity Building Grants support established 501(c)(3) organizations in Greenville County, SC, aiming to enhance their operational capabilities and governance. Funding opportunities include projects for client engagement, management innovation, collaborative ventures, technology improvements, and revenue diversification. Examples of capacity building encompass financial planning, organizational assessments, strategic planning, and leadership development. Grants are awarded competitively, allowing one application per agency per year, excluding individuals and certain ineligible expenses.

The Hollingsworth Funds Grant aims to support nonprofit organizations in Greenville County that work towards removing systemic barriers based on race, place, and socioeconomic status. The grants focus on strengthening pathways to career opportunities, enhancing educational outcomes, and improving access to essential services like affordable housing and transportation. With a commitment to equity, the fund encourages proposals that align with its vision of creating a just and inclusive community where all individuals can thrive.

The Robert B. and Ruth K. Lee Foundation Grant aims to enhance the quality of life in Greenville County, South Carolina. Established in 2000, the foundation supports diverse areas including arts, education, health, and human services. With no geographic limitations, it primarily funds programs benefiting the local community. Grants typically range from $2,000 to $5,000, emphasizing initiatives for the elderly, children’s programs in the arts, and literary projects. Organizations must be 501(c)(3) exempt to be eligible.

The Educational Foundation of America (EFA) supports the Reproductive Health & Justice Grant Program to enhance access to abortion and contraception throughout the U.S., particularly in Appalachia, Alabama, and Florida. EFA funds innovative organizations that advocate for reproductive rights, provide direct support to abortion services, and leverage impact investing strategies. This commitment aims to ensure reproductive freedom, foster equity, and promote sustainability in underserved communities.

The Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative aims to revitalize communities impacted by coal industry transitions. This initiative provides funding for projects that diversify local economies, enhance job training, and create new employment opportunities. By fostering collaboration among various stakeholders, the POWER Initiative supports strategic investments that align with regional economic development plans, ensuring a more resilient future for coal-affected areas.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Engineering

PLTW Engineering students adopt a problem-solving mindset, are engaged in compelling, real-world challenges that help them become better collaborators and thinkers, and are prepared with skills to step into any career path they take. Each PLTW Engineering course engages students in interdisciplinary activities like working with a client to design a home, programming electronic devices or robotic arms, or exploring algae as a biofuel source. These activities not only build knowledge and skills in engineering, but also empower students to develop essential skills such as problem solving, critical and creative thinking, communication, collaboration, and perseverance.

PLTW Engineering - New Program (3M) 

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

Greenville Women Giving (GWG) is a philanthropic organization in Greenville County, SC, focused on funding impactful community projects. Grants are awarded annually based on member voting and emphasize areas such as Arts, Education, Environment, Health, and Human Services. Organizations must be tax-exempt and serve Greenville County. GWG prioritizes high-impact initiatives that foster collaboration and measurable outcomes, with a commitment to addressing community needs without discrimination. The application deadline is at the end of November each year.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Computer Science

PLTW Computer Science students are technology trailblazers who are empowered through transportable skills and prepared to start their career, whether that is in computer science or not. Empower your students to become creators of the technology all around them. PLTW Computer Science engages students in collaborative projects that help them develop in-demand computer science knowledge as well as transportable skills like creative thinking and communication. And whether they’re creating an online art gallery or using automation to process and analyze DNA-sequence data, PLTW Computer Science students are seeing how their learning connects to the real world.

PLTW Computer Science - New Program (3M)

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

Project Lead the Way (PLTW) provides innovative, hands-on learning experiences for students in PreK-5, fostering confidence and career readiness. With support from 3M, PLTW Launch aims to enhance STEM education by increasing exposure, supporting experiential learning, and improving teaching quality. This partnership ensures that students and teachers have the necessary tools and resources to thrive in a rapidly evolving world, empowering the next generation of leaders in science and technology.

The F. W. Symmes Foundation Grant aims to enhance the quality of life for residents of Greenville County, South Carolina, by supporting charitable, educational, and cultural initiatives. Established by Fred W. Symmes, the foundation prioritizes organizations that align with its mission and are recognized as 501(c)(3) exempt entities. With a minimum grant request of $20,000, the foundation focuses on impactful projects, particularly capital improvements, while ensuring financial sustainability for ongoing programs.

The Housing for Everyone Grant Competition, part of the 2026 Initiative, aims to support eviction prevention in low-to moderate-income communities. This 20th annual initiative recognizes the destabilizing impact of eviction and displacement on families, which leads to job loss, school disruptions, and health issues. By funding innovative organizations, the competition seeks to provide stability for renters, enabling them to stay in their homes and communities.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Gateway

PLTW Gateway (6-8) opens paths that create meaningful futures. It connects students to careers in areas they can, and can't, imagine. Through explorations of skilled trades, coding and robotics, flight and space, human body systems, and more, PLTW Gateway fuels students’ passion for discovery. As they engage in hands-on, collaborative problem solving focused on real-world challenges, students use and stretch their imaginations in brand-new ways that connect their learning to life. All the while, students step into roles spanning the career landscape—a crucial experience during this transitional time in their lives, long before they enter their degreed or skilled trade professions. 

PLTW Gateway - Program Expansion (3M)

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

Project Lead the Way inc.

School and district leaders need a solution that cultivates confidence and career readiness—and PLTW checks all the boxes. As a nonprofit organization founded by educators and driven by education leaders, we've spent more than 28 years equipping students with the technical knowledge, transferable skills, and career confidence they need to thrive—through programs that integrate real-world industry partnerships, best-in-class teacher training, and our proven activity-, project-, problem-based (APB) instructional model. At PLTW, we're on a mission to create a transformative learning environment and empower students to develop in-demand knowledge and skills necessary to thrive in an evolving world. 

PLTW Launch (PreK-5)

Young learners are naturally wired for discovery. PLTW Launch is designed with activities that let them see what they can be and build skills to discover what they can do. Students are immersed in hands-on activities, projects, and problems that build upon each other and relate to the real world. They experience integrated learning that blends computer science, engineering, biomedical science, and more. Throughout the modules, even the youngest learners apply their math and English Language Arts (ELA) skills, learn science to standards, and adopt skills that are foundational across disciplines.

PLTW Launch - Program Expansion (3M)

3M forms lasting partnerships with communities and provides resources to help them succeed and grow – ensuring a more interconnected and thriving world. 3M inspires the next generation of science leaders through the following goals:

• Increasing STEM exposure in K-12 classrooms
• Supporting experiential learning opportunities
• Enhancing the quality of STEM teaching
• Providing professional development opportunities for students

3M has partnered with PLTW to ensure students and teachers have the tools, resources and knowledge they need to succeed in STEM.

The Indigo Hope Foundation offers grants to organizations in the Upstate of South Carolina, focusing on addiction, homelessness, at-risk youth, veterans, and first responders. They award between $250 and $100,000, prioritizing projects that demonstrate measurable results and address critical community needs. Eligible applicants must be 501(c)(3) tax-exempt or government units, with only one application allowed per grant period. The foundation emphasizes collaboration and favors faith-based organizations.

The Area Development Grant Program, managed by the Appalachian Regional Commission (ARC), supports economic growth in Appalachia through investments in critical infrastructure and workforce development. Targeting 423 counties across 13 states, the program encourages local communities to collaborate with state governments to identify and implement impactful projects. Key focus areas include enhancing utilities, promoting entrepreneurship, and strengthening local leadership. This initiative aims to uplift the 26 million residents of Appalachia, fostering sustainable economic opportunities.

The ARISE Grants, offered by the Appalachian Regional Commission, aim to drive regional economic transformation across 13 Appalachian states. With funding of up to $63.5 million for implementation grants and $10 million maximum awards, the initiative supports collaborative projects that enhance community capacity and economic growth. The program encourages innovative partnerships to strengthen local economies and achieve socioeconomic parity, benefiting over 26 million residents in the Appalachian Region.

BASF Corporation, a leading chemical company based in Florham Park, New Jersey, is committed to charitable giving that aligns with its corporate social responsibility goals. The focus areas include science education, environmental sustainability, and health and safety. Donations are only made to eligible non-profit organizations under the U.S. Internal Revenue Code, ensuring that contributions support initiatives that enhance the quality of life in BASF communities and promote a sustainable future.

Truliant's Community Giving program supports nonprofit organizations that enhance local communities near Truliant branches. Focus areas include financial wellness, social mobility, and workforce education, specifically targeting initiatives that promote financial literacy, basic stability, and career development. Eligible organizations must be 501(c)(3) tax-exempt and have been operational for at least three years. The program seeks to empower individuals and families while fostering community growth and stability.

The W. W. Burgiss Charities Grant supports initiatives focused on religion, education, and assistance for the needy in Greenville County, South Carolina. Established by W. W. Burgiss in 1925, the foundation prioritizes capital needs and one-time special projects, aiming to create measurable impacts. Eligible organizations must be 501(c)(3) exempt and demonstrate financial sustainability. With an average grant size of $12,000, the foundation aims to uplift the sick and underprivileged, ensuring local community enhancement through targeted funding.

The Metropolitan Arts Council (MAC) offers the Arts Organization Quarterly Project Grant Program, prioritizing projects that enhance community impact through arts. Funding up to $3,000 with a 2:1 match encourages initiatives supporting artists, promoting cultural tourism, and ensuring access to the arts for all. This grant facilitates economic growth and aims to attract new audiences to artistic programming, fostering a vibrant cultural landscape in Greenville.

Spectrum Digital Education Grants support nonprofit organizations in educating communities about broadband benefits and usage. These grants aim to bridge the digital divide, particularly for seniors and those with disabilities or ethnically diverse backgrounds. Applicants must demonstrate community partnership, address specific needs, and provide measurable impact metrics. With a focus on financial feasibility and meaningful outcomes, this initiative ensures that underrepresented urban and rural communities gain access to essential digital resources, fostering long-term improvement in their lives.