US Bancorp Foundation Grants for Nebraska Communities
With a mission to strengthen communities, US Bancorp Foundation provides Nebraska nonprofits with funding for economic and workforce advancement, safe and affordable housing, and community arts and culture. 501(c)(3) organizations, especially those led by people of color and addressing multiple pillars like work, home, and play, may be eligible to support community health and stability initiatives.
US Bancorp Foundation
Health and Youth Program Funding from Costco Foundation
Nonprofit organizations in Nebraska supporting children, education, or health and human services can apply for monetary program support, which may include rare disease initiatives. With a mission to strengthen community well-being, Costco Foundation provides 501(c)(3) nonprofits with grants reviewed within 4–6 weeks, prioritizing measurable outcomes and strong community collaboration.
Costco Foundation
Dan Paul Foundation Grants for Youth Programs
Nonprofit 501(c)(3) organizations serving youth through health, education, development, or welfare programs in Nebraska and beyond can seek funding for direct services, advocacy, and enrichment initiatives. The Dan Paul Foundation provides up to US $15,000 for projects such as child welfare, early childhood development, environmental responsibility, homelessness, poverty, and refugee enrichment, which may benefit rare disease–affected children and families.
The Dan Paul Foundation
Social Impact Funding from Draper Richards Kaplan Foundation
Early-stage, impact-first nonprofits and mission-driven for-profits in Nebraska and globally can apply for Draper Richards Kaplan Foundation support, with awards up to US $300,000 over three years for scalable social or environmental solutions. Organizations addressing underserved communities, including those working on rare or respiratory diseases, must show post-pilot traction, measurable impact, and strong growth potential.
Draper Richards Kaplan Foundation
Cisco Systems Foundation Social Impact Grants in Nebraska
Nonprofit and nongovernmental organizations using technology to address crisis response, education access, or economic empowerment in Nebraska and beyond can apply for Global Impact Cash Grants, with awards up to US $100,000. Grants from Cisco Systems Foundation help tech-enabled programs serving mostly economically underserved communities, including initiatives that may support rare disease-affected populations through education or economic stability.
Cisco Systems Foundation
State Farm Foundation Grants for Nebraska Safety
Grants from State Farm Companies Foundation help Nebraska educational institutions, government programs, and eligible nonprofits fund safety, education, and community development initiatives. Organizations working on auto and home safety, disaster preparedness and recovery, affordable housing, job training, financial literacy, food insecurity, or K–12 and higher education programs may be eligible to apply.
State Farm Companies Foundation
Nebraska Arts Education Funding via Hearst Foundation
Nonprofit cultural institutions in Nebraska offering arts, science, or STEAM education programs can access funding through the William Randolph Hearst Foundation, with typical awards of More than US $100,000. U.S.-based 501(c)(3) organizations with audited expenses above $2 million may be eligible for program, capital, or limited general support that could complement rare disease outreach or education efforts.
William Randolph Hearst Foundation
Labcorp Charitable Foundation Grants for Nebraska Health
Nebraska 501(c)(3) and equivalent charitable organizations working in health, education, or community services can seek funding for programs such as healthcare access, food pantries, and STEM education. Labcorp Charitable Foundation supports initiatives including patient services for underserved populations and health-related programming, which may benefit organizations addressing respiratory and other rare diseases.
Labcorp Charitable Foundation
Nebraska Youth Poverty Funding via Michael & Susan Dell Foundation
Nonprofits, social enterprises, schools, and public entities working on education, child health, or family economic stability for low-income urban youth in Nebraska can seek project or scaling support; awards are more than US $50,000. With a mission to expand opportunity, Michael & Susan Dell Foundation funds work in the U.S., India, and South Africa that measurably improves children’s lives and may benefit rare disease initiatives serving these populations.
Michael & Susan Dell Foundation
Roche Support for Global Community Programs
Nonprofit charities running humanitarian, social, educational, environmental, or arts programs in countries where Roche operates, including Nebraska via its U.S. affiliate, may be eligible for philanthropic support. With a mission to strengthen communities, Roche provides accredited charities with funding for sustainable development projects, disaster response, youth science education, community health, and contemporary arts initiatives.
La Roche, Inc.
Semnani Family Foundation Support for Health Programs
Nebraska health and human services organizations serving marginalized or vulnerable people can access funding through Semnani Family Foundation for programs in health care access, disease-related services, and humanitarian aid. Projects that address medical needs, child and women’s health, or social services for underserved communities may be competitive within this global funding portfolio.
Semnani Family Foundation
Broad Program Funding for Nonprofits from Sidney Stern Memorial Trust
Nebraska 501(c)(3) organizations working in charitable, scientific, medical, or educational areas can access funding through the Sidney Stern Memorial Trust to support programs serving U.S.-based populations. Eligible nonprofits with respiratory or rare disease initiatives may be competitive if they demonstrate strong management, broad impact, and meaningful contributions to community welfare.
Sidney Stern Memorial Trust
Self-Reliance Program Funding for Nonprofits from Gupta Family Foundation
Applications due Jul 31, 2026
Nonprofit organizations working to help disadvantaged people become self-reliant, including those addressing poverty, disability, social exclusion, or disaster relief, may be eligible for support, including in Nebraska. Nebraska health and rare-disease organizations can access funding through Gupta Family Foundation, with annual or multi-year awards ranging from US $5,000 - US $250,000 for smaller organizations operating in eligible countries.
Gupta Family Foundation
Nebraska Community Funding via Hansen Family Foundation
Applications due Sep 11, 2026
Nonprofit 501(c)(3) organizations working on children’s services, education, humanitarian aid, environmental programs, animal welfare, or arts and culture in Nebraska and beyond can seek project or program support, with typical awards of US $1,000 - US $10,000. With a mission to uphold life, liberty, and the pursuit of happiness, Hansen Family Foundation considers U.S.-based applicants under $1 million in annual budget.
Hansen Family Foundation
Jesse W Couch Foundation Grants for Storytelling
Applications due Sep 25, 2026
Nonprofit 501(c)(3) organizations and aligned for-profits can seek the Storytelling Grant to share the impact of their preservation, education, or wellness work, including in Nebraska. With a mission to support community-focused initiatives, Jesse W Couch Charitable Foundation provides more than US $50,000 to help capture and communicate meaningful change, which may benefit rare disease–related programs.
Jesse W Couch Charitable Foundation
Robinson Foundation Health Grants in Nebraska
Applications due Oct 15, 2026
Nebraska 501(c)(3) organizations providing medical assistance, health services, or related humanitarian support can apply for single-year project funding that creates tangible impact. Focused on relieving hardship, the Robinson Foundation invites Southern-region nonprofits active for more than three years to seek support, which may benefit programs serving patients with rare or respiratory diseases.
Robinson Foundation
Community and Environmental Funding from Dudley T Dougherty Foundation
Applications due Oct 31, 2026
Nebraska nonprofits working on community services, environmental conservation, or peacebuilding can access funding through the Dudley T Dougherty Foundation to support their 501(c)(3) charitable programs. Organizations focused on rare or respiratory diseases may be eligible if their work intersects with these broader community or environmental priorities.
Dudley T Dougherty Foundation Inc
Georgia-Pacific Foundation Support for Community Programs
Applications due Oct 31, 2026
Nonprofit organizations, public schools, and local government entities near Georgia-Pacific manufacturing communities can seek funding for education, environment, entrepreneurship, and community enrichment projects in Nebraska and other eligible areas. Focused on strengthening local well-being, Georgia-Pacific Foundation invites community-based programs that align with its mission and operate within 30 miles of a GP facility.
Georgia-Pacific Foundation
TJX Foundation Grants for Nebraska Youth Programs
Letter of inquiry due Oct 31, 2026
Nebraska 501(c)(3) nonprofits located within 15 miles of a TJX store, distribution center, or office can seek funding for basic needs, at-risk youth enrichment, workforce readiness, and domestic violence safety programs. Grants from TJX Foundation help organizations serving vulnerable children and families, including those facing serious health challenges, which may benefit some rare disease support efforts.
The Tjx Foundation Inc
Nebraska Community Services Funding via Lawrence Foundation
Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations, public schools, and libraries in Nebraska seeking support for environmental or human services programs can apply for unrestricted grants from Lawrence Foundation, typically ranging from US $5,000 - US $10,000. Eligible organizations working on rare disease–related services within these areas of interest may benefit from either program or general operating support.
Lawrence Foundation
Community Program Grants for Nonprofits from Dreyfus Foundation
Applications due Nov 11, 2026
Nonprofit organizations in Nebraska and across the U.S. seeking support for community programs can apply for US $1,000 - US $20,000 to fund projects where modest grants make a big impact. Max and Victoria Dreyfus Foundation considers museums, cultural and performing arts, education, health facilities, environmental and wildlife efforts, and services for youth, seniors, and people with disabilities, which may include rare disease-related initiatives.
Max and Victoria Dreyfus Foundation
Basic Needs and Community Grants from Ameriprise
Applications due Jan 15, 2027
U.S.-based 501(c)(3) nonprofits addressing basic needs, community vitality, or volunteer-driven causes can receive funding from Ameriprise Financial to support programs like hunger relief, shelter, adult self-sufficiency, and community development. Nebraska organizations working on economic stability or supportive services may be eligible, with priority for those engaging Ameriprise employees or advisors as volunteers.
Ameriprise Financial
Broad Program Funding for Nonprofits from Dr Scholl Foundation
Letter of inquiry due Jan 31, 2027
Nebraska 501(c)(3) nonprofits seeking project support in education, health care, social services, civic or cultural work, or environmental programs can access funding through Dr Scholl Foundation. Grants of US $5,000 - US $25,000 are awarded annually, with an online LOI and application required during the October 1 to March 1 grant cycle.
Dr Scholl Foundation
Nebraska Community Health Funding via O'Reilly Automotive Foundation
Applications due Apr 15, 2027
Nonprofit 501(c)(3) organizations in Nebraska working to improve community health, stability, and services can access funding through O'Reilly Automotive Foundation for project, general operating, or capital support. U.S.-based charities serving underserved people through health and social services, economic stability, workforce development, or disaster relief may be eligible, including programs intersecting with respiratory or rare disease needs.
O'Reilly Automotive Foundation Inc
Union Pacific Foundation Community Grants in Nebraska
Applications due Apr 30, 2027
Nebraska 501(c)(3) public charities can seek US $5,000 - US $30,000 for safety, workforce development, community vitality, or environmental sustainability projects that primarily benefit Union Pacific–served communities. Grants from Union Pacific Foundation help nonprofits, including independent emergency response organizations, expand direct services and capacity, with an emphasis on diversity, equity, and inclusion for underrepresented populations.
Union Pacific Foundation
Nebraska Youth Services Funding via Chick Fil A Foundation
Applications due May 1, 2027
Nonprofit 501(c)(3) organizations in Nebraska serving youth and families through education, housing, food security, or environmental programs can apply for Chick Fil A Foundation’s True Inspiration Awards, with grants of US $30,000 - US $350,000. Programs supporting underserved young people, including those affected by rare diseases, may be competitive across the four award categories.
Chick Fil A Foundation Inc