Costco Foundation Grants for Pennsylvania Health
Pennsylvania 501(c)(3) nonprofits supporting children, education, or health and human services can seek monetary program funding that may benefit rare disease initiatives. Focused on community impact, Costco Foundation invites organizations to apply for charitable contributions that demonstrate measurable outcomes, strong community collaboration, and a broad base of financial support in areas where Costco operates.
Costco Foundation
Creag Foundation Support for Innovative Health Programs
Nonprofit 501(c)(3) organizations with innovative approaches to health and human services can seek funding to address social problems, including rare and respiratory diseases, in Pennsylvania and beyond. Grants from Creag Foundation help smaller or evolving organizations pilot new solutions to existing or previously unaddressed issues through invited proposals and letters of inquiry.
Creag Foundation
Pennsylvania Youth Welfare Funding via Dan Paul Foundation
Nonprofit 501(c)(3) organizations supporting youth health, education, development, or welfare in Pennsylvania can receive up to US $15,000 for direct-service programs. The Dan Paul Foundation funds initiatives such as child advocacy, homelessness and poverty services, environmental education, clean air and water, refugee enrichment, and scholarships, which may benefit youth affected by complex or rare health conditions.
The Dan Paul Foundation
Draper Richards Kaplan Foundation Grants for Startups
Early-stage, impact-first nonprofits and mission-driven startups tackling social or environmental challenges can receive up to US $300,000 from Draper Richards Kaplan Foundation, including organizations in Pennsylvania. With a mission to dramatically improve lives, the foundation provides multi-year capital plus intensive capacity-building support to help scalable models grow and reach underserved communities.
Draper Richards Kaplan Foundation
Pennsylvania Economic Empowerment Funding via Cisco
Nonprofit and nongovernmental organizations using technology for crisis response, education access, or economic empowerment projects in Pennsylvania can access funding through Cisco Systems Foundation’s Global Impact Cash Grants, with awards up to US $100,000. Eligible programs must primarily serve economically underserved communities and focus on innovative, early-stage solutions that improve reach and efficiency of services.
Cisco Systems Foundation
Community Safety and Education Grants from State Farm
Educational institutions, government programs, 501(c)(3) nonprofits, and 501(c)(4) volunteer fire companies can seek funding for safety, education, and community development initiatives from State Farm Companies Foundation. Pennsylvania organizations working on issues like community safety, disaster preparedness, housing, job training, or education may be eligible through this invitation-only community grant process.
State Farm Companies Foundation
Health and Community Grants for Nonprofits from Labcorp Charitable Foundation
U.S.-based 501(c)(3) organizations working in health and welfare, education, or community services can apply for grants from Labcorp Charitable Foundation to support programs like healthcare access, food pantries, STEM education, and preventative health. Pennsylvania nonprofits addressing rare or chronic disease care within these areas may be eligible.
Labcorp Charitable Foundation
PNC Foundation Support for Community Development
Nonprofit 501(c)(3) organizations working on early childhood education or community economic development in Pennsylvania communities served by PNC can seek funding for programs and services. With a mission to strengthen and enrich local communities, PNC Foundation provides grants for education, affordable housing, community revitalization, arts and culture, and essential services for low- and moderate-income families, which may benefit rare disease populations.
PNC Foundation
Humanitarian and Health Funding for Charities from Roche
Pennsylvania charities running humanitarian, social development, science education, community, or contemporary arts projects can access funding through Roche, which supports accredited, high-quality initiatives worldwide. Programs that promote sustainable development, engage local partners and employees, and operate within a single country may be eligible through Roche’s local affiliate structure.
La Roche, Inc.
Health and Humanitarian Grants for Nonprofits from Semnani Family Foundation
Nonprofit organizations providing health, education, or humanitarian services can apply for support from Semnani Family Foundation, including those in Pennsylvania. The foundation funds programs for marginalized communities worldwide, such as disease prevention, children’s and women’s health, vaccines, and disaster relief. U.S.-based health and human services initiatives may be eligible if they advance human welfare for vulnerable populations.
Semnani Family Foundation
Pennsylvania Health Funding via Sidney Stern Memorial Trust
Pennsylvania 501(c)(3) health, medical, scientific, and educational organizations can access funding through the Sidney Stern Memorial Trust for programs serving people in the U.S. Projects must use funds within the country and come from tax-exempt charities; rare disease initiatives that fit these priorities may be eligible.
Sidney Stern Memorial Trust
Bank of America Support for Community Programs
Pennsylvania 501(c)(3) nonprofits working on community development, basic needs, workforce education, arts, environment, or inclusion can access funding through Bank of America Foundation’s sponsorship program. Organizations addressing housing, jobs, hunger, or community life, including rare disease groups with related economic or social initiatives, may be eligible for regional sponsorship support.
Bank Of America Charitable Foundation Inc
Gupta Family Foundation Support for Disadvantaged
Applications due Jul 31, 2026
Nonprofit organizations helping disadvantaged people become self-reliant can apply for Gupta Family Foundation’s grants, awarding US $5,000 - US $250,000 for focused intervention and humanitarian relief. Eligible 501(c)(3)s and similar organizations in the U.S. and select countries, including those serving Pennsylvania communities, may benefit if they meet the foundation’s size, leadership, and non-sectarian criteria.
Gupta Family Foundation
Hansen Family Foundation Grants for Pennsylvania Programs
Applications due Sep 11, 2026
Pennsylvania 501(c)(3) nonprofits with budgets under $1 million can access funding for children, education, animals, environment, humanitarian aid, and arts and culture projects. Grants from the Hansen Family Foundation range from US $1,000 - US $10,000 and may benefit organizations whose rare disease work overlaps with these humanitarian or basic human needs priorities.
Hansen Family Foundation
Storytelling Funding from Jesse W Couch Foundation
Applications due Sep 25, 2026
Nonprofit 501(c)(3) organizations and aligned for-profits in the U.S., including Pennsylvania, can seek the Storytelling Grant to share the impact of their work through compelling narratives. Jesse W Couch Charitable Foundation supports projects tied to preservation, education, or wellness, which may include programs serving people affected by rare or respiratory diseases.
Jesse W Couch Charitable Foundation
Health and Human Services Funding from Robinson Foundation
Applications due Oct 15, 2026
Nonprofit 501(c)(3) organizations providing health, medical assistance, or humanitarian services can seek support for single-year projects from the Robinson Foundation, serving communities across the Southern U.S. Grants from Robinson Foundation help programs addressing medical needs, poverty, disaster relief, or family and youth services that demonstrate fiscal responsibility and clear, tangible impact; Pennsylvania-based orgs serving southern regions may be eligible.
Robinson Foundation
Pennsylvania Community Services Funding via Insperity
Applications due Oct 16, 2026
Pennsylvania 501(c)(3) nonprofits seeking support for community services or fundraising events can access funding through Insperity, which offers philanthropic grants and event sponsorships in select counties including Allegheny and Philadelphia. Eligible charities must connect to Insperity employees or clients, or serve communities where employees live and work, and may include organizations addressing rare or respiratory diseases.
Insperity
Youth and Basic Needs Funding from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations within 15 miles of a TJX store, distribution center, or office in Pennsylvania can apply for The Tjx Foundation’s grants supporting basic needs, youth education, workforce readiness, and safety from domestic violence. Programs serving vulnerable families and children, including those affected by serious or rare diseases, may be eligible after completing an eligibility questionnaire and LOI.
The Tjx Foundation Inc
Lawrence Foundation Support for Community Services
Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations, public schools, and libraries seeking support for environmental or human services programs, including work in Pennsylvania, can apply for unrestricted grants of US $5,000 - US $10,000. Focused on environment and human services, the Lawrence Foundation funds general operating or project costs, which may include rare disease–related community services where aligned with its priorities.
Lawrence Foundation
Max and Victoria Dreyfus Foundation Support for Community Programs
Applications due Nov 11, 2026
Nonprofit organizations in Pennsylvania and across the U.S. can apply for US $1,000 - US $20,000 to support community-based programs and facilities. Grants from Max and Victoria Dreyfus Foundation help organizations working in areas like health facilities, education, disability and senior services, and related community services that may include rare disease initiatives.
Max and Victoria Dreyfus Foundation
Basic Needs Funding for Nonprofits from Ameriprise Financial
Applications due Jan 15, 2027
Nonprofit 501(c)(3) organizations in the U.S. working on hunger, shelter, adult self-sufficiency, or community vitality projects may be eligible for Ameriprise Financial support. Focused on basic needs and community development, Ameriprise Financial invites programs with strong volunteer engagement, which can include Pennsylvania initiatives serving vulnerable populations or complementing rare disease support services.
Ameriprise Financial
Dr Scholl Foundation Health Grants in Pennsylvania
Letter of inquiry due Jan 31, 2027
Pennsylvania 501(c)(3) nonprofits working on health care, education, social services, civic or cultural, or environmental programs can access funding through Dr Scholl Foundation. Grants of US $5,000 - US $25,000 are awarded annually, primarily to U.S. applicants, and may benefit organizations addressing respiratory and other rare disease needs.
Dr Scholl Foundation
Rare Disease Research Grants for Scientists from Orphan Disease Center
Letter of inquiry due Feb 20, 2027
Researchers working on CDKL5 Deficiency Disorder can apply for one-year pilot grants of US $150,000 from the Orphan Disease Center to advance treatment-focused studies. With a mission to develop transformative therapies for rare diseases, this Pennsylvania-based center supports basic and translational work that moves toward potential therapies for CDKL5-related neurological conditions.
University of Pennsylvania’s School of Medicine: Orphan Disease Center (ODC)
Foundation for Enhancing Communities Grants for Pennsylvania Students
Applications due Mar 15, 2027
Pennsylvania high school seniors pursuing college or trade school can receive up to US $2,500 for higher education costs through the Nick Pantalone Memorial Scholarship Fund. The Foundation for Enhancing Communities provides this one-time award for students in specified south-central counties who have financial need, a 3.0 GPA, and a connection to cancer or Mini-Thon.
The Foundation for Enhancing Communities
Orphan Disease Center Support for Rare Diseases
Letter of inquiry due Apr 18, 2027
Research institutions and investigators studying rare genetic and neurological conditions in Pennsylvania can apply for the Orphan Disease Center’s CSNK2A1 Pilot Grant Program; awards US $50,000 for projects on OCNDS and CSNK2A1 biology. Funding supports disease mechanisms, biomarker discovery, and therapeutic approaches, including work on speech, intellectual disability, sleep, and anxiety symptoms.
University of Pennsylvania’s School of Medicine: Orphan Disease Center (ODC)
Chick Fil A Foundation Grants for Youth
Applications due May 1, 2027
Nonprofit 501(c)(3) organizations in Pennsylvania working on youth education, basic needs, or community and environmental programs can apply for Chick Fil A Foundation’s True Inspiration Awards, with grants of US $30,000 - US $350,000. Programs serving underserved children and families, including those affected by rare diseases, may be eligible.
Chick Fil A Foundation Inc
Community Partnership Grants for Nonprofits from Mutual of America Foundation
Applications due Jul 1, 2027
Nonprofit organizations in Pennsylvania with strong, replicable community partnerships addressing significant social issues can apply for Mutual of America Foundation’s national Community Partnership Award. This U.S.-wide competition honors collaborations among public, private, and social sector partners that measurably improve communities and may benefit programs related to rare or respiratory diseases.
Mutual Of America Foundation