South Dakota Community Programs Funding via US Bancorp Foundation
South Dakota 501(c)(3) nonprofits working on economic and workforce advancement, affordable housing, or community arts and culture can access funding through the US Bancorp Foundation’s Community Possible program. Organizations in designated U.S. Bank communities, especially those led by people of color and addressing multiple pillars of work, home, and play, may be competitive.
US Bancorp Foundation
Creag Foundation Innovation Grants in South Dakota
Nonprofit 501(c)(3) organizations with innovative human services or social problem–solving programs in South Dakota can seek funding to develop or expand their work. Focused on new approaches to societal issues, Creag Foundation invites letters of inquiry from eligible groups, which may include organizations working on global health–related challenges.
Creag Foundation
Youth and Child Welfare Funding from Dan Paul Foundation
501(c)(3) nonprofits serving youth and children’s health, education, development, or welfare can apply for Dan Paul Foundation grants, including organizations in South Dakota. Awards up to US $15,000 support programs such as early childhood development, child advocacy, homelessness and poverty services, refugee enrichment, environmental education, and related youth-focused initiatives.
The Dan Paul Foundation
Draper Richards Kaplan Foundation Grants for Global Health
Early-stage nonprofit and impact-first social enterprises working on scalable social or environmental solutions in South Dakota and globally can access funding through Draper Richards Kaplan Foundation; awards up to US $300,000 over three years for capacity, capital, and community support. Organizations must serve underserved populations and demonstrate measurable, scalable impact potential.
Draper Richards Kaplan Foundation
Tech-Enabled Social Impact Funding from Cisco
Nonprofits and NGOs using technology for crisis response, education access, economic empowerment, or climate resilience worldwide, including South Dakota, can seek Global Impact Cash Grants supporting innovative programs for underserved communities. Cisco Systems Foundation offers up to US $100,000, with year-round applications beginning with a brief Letter of Inquiry.
Cisco Systems Foundation
Community Safety and Education Grants from State Farm
South Dakota educational institutions, government programs, 501(c)(3) nonprofits, and 501(c)(4) volunteer fire companies can access funding through State Farm for safety, education, and community development initiatives. Programs such as disaster preparedness, community revitalization, job training, STEM education, and efforts addressing food insecurity or financial literacy may be eligible, including those with a global health dimension.
State Farm Companies Foundation
Hearst Foundation Culture Grants in South Dakota
South Dakota cultural nonprofits offering arts, science, or arts education programming can access funding through the William Randolph Hearst Foundation for program, capital, and limited general or endowment support. U.S.-based 501(c)(3) organizations with audited expenses over $2 million, strong impact, and broad reach may be competitive, including those whose cultural work intersects with global health themes.
William Randolph Hearst Foundation
South Dakota Social Service Funding via Hearst Foundation
South Dakota social service nonprofits tackling chronic poverty and economic hardship can access funding through William Randolph Hearst Foundation for program, capital, or general support. U.S.-based 501(c)(3) organizations with audited expenses over $2 million, strong outcomes, and scalable models—especially in housing, food access, jobs, reentry, youth, or legal services—may be awarded more than US $100,000.
William Randolph Hearst Foundation
South Dakota Health Programs Funding via Labcorp
Nonprofit organizations working on health, education, or community services in South Dakota can access funding via Labcorp Charitable Foundation to support healthcare access, food pantries, STEM programs, and related services. Eligible applicants are U.S.-based 501(c)(3) organizations or those with equivalent charitable status; global health-focused programs may be eligible if they fit these priorities.
Labcorp Charitable Foundation
Michael & Susan Dell Foundation Youth Grants in South Dakota
Organizations serving children and youth from urban low-income communities in South Dakota can apply for Michael & Susan Dell Foundation grants of more than US $50,000 for project support or scaling. Eligible entities include nonprofits, social enterprises, schools, governments, and other public-benefit organizations working in education, children’s health, or family economic stability within the U.S., India, or South Africa.
Michael & Susan Dell Foundation
Global Health and Relief Funding from Semnani
Nonprofits and humanitarian organizations working on global health, education, or disaster relief can seek support for marginalized communities worldwide, including work connected to South Dakota. Semnani Family Foundation provides funding for health care access, women and children’s health, humanitarian aid, and related social services projects serving vulnerable populations internationally and in the U.S.
Semnani Family Foundation
Sidney Stern Memorial Trust Grants for South Dakota Health
Nonprofit 501(c)(3) organizations working in health, medical, scientific, educational, or other charitable fields in South Dakota can seek funding to support programs that benefit people in the U.S. With a mission to strengthen charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides support to soundly managed organizations serving broad populations, which may include global health–oriented initiatives based in the state.
Sidney Stern Memorial Trust
Bank of America Support for Community Programs
Nonprofit 501(c)(3) organizations working on basic needs, workforce development, housing, arts, environment, or inclusion in South Dakota can seek sponsorship support that advances economic mobility and community vitality. Bank of America Foundation’s regional sponsorships may benefit global health–related efforts that address hunger, shelter, or broader community development priorities.
Bank Of America Charitable Foundation Inc
South Dakota Poverty Services Funding via Gupta Family Foundation
Applications due Jul 31, 2026
Non-sectarian human and social service nonprofits addressing disadvantage and self-reliance can apply for Gupta Family Foundation grants, with awards from US $5,000 - US $250,000. With a mission to help disadvantaged people become self-reliant, Gupta Family Foundation provides funding to smaller organizations, including U.S.-based 501(c)(3)s, working in areas like poverty alleviation, disability services, and humanitarian relief.
Gupta Family Foundation
Cowles Charitable Trust Support for Health Programs
Applications due Sep 1, 2026
U.S. 501(c)(3) charitable organizations working in health, education, social justice, or the arts, including those with global health programming in South Dakota, can apply for the Cowles Charitable Trust’s grants of up to US $10,000. Funding may support program costs or general operating support, with occasional consideration for national and international efforts.
Cowles Charitable Trust
Hansen Family Foundation Humanitarian Grants in South Dakota
Applications due Sep 11, 2026
South Dakota 501(c)(3) nonprofits addressing humanitarian needs, education, children, animals, environment, or arts can access funding through the Hansen Family Foundation, with awards ranging from US $1,000 - US $10,000. Eligible U.S.-based organizations with budgets under $1 million may support global health-related services as part of their broader humanitarian or basic needs work.
Hansen Family Foundation
South Health Funding via Robinson Foundation
Applications due Oct 15, 2026
South Dakota health and humanitarian nonprofits can access funding through Robinson Foundation for programs in medical assistance, poverty relief, disaster response, and related services. Eligible applicants are 501(c)(3) public charities active for over three years, seeking single-year program support and primarily serving communities in the Southern region below the Mason-Dixon line.
Robinson Foundation
Dudley T Dougherty Foundation Support for Community Services
Applications due Oct 31, 2026
Focused on community services and environmental initiatives, this grant invites South Dakota 501(c)(3) organizations to seek support for charitable programs. The Dudley T Dougherty Foundation funds nonprofit projects that respect people, the environment, and global well-being, which may include organizations working on international or global health-related efforts.
Dudley T Dougherty Foundation Inc
Youth and Basic Needs Grants from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations supporting basic needs, at-risk youth, workforce readiness, or safety from domestic violence near South Dakota TJX locations can seek program funding through The TJX Foundation. Grants may benefit global health–related efforts that help vulnerable families and children access food, shelter, education, training, or safety resources within 15 miles of a TJX site.
The Tjx Foundation Inc
Lawrence Foundation Support for Environmental Programs
Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations, public schools, and libraries can seek $5,000 - $10,000 in unrestricted operating or program support for environmental and human services work, including organizations in South Dakota. With a mission to support environmental and human services causes, Lawrence Foundation provides flexible funding that can include reasonable indirect costs for eligible global or local initiatives.
Lawrence Foundation
Max and Victoria Dreyfus Foundation Grants for South Dakota Community Programs
Applications due Nov 11, 2026
Max and Victoria Dreyfus Foundation provides South Dakota nonprofits with US $1,000 - US $20,000 to support museums, cultural and performing arts programs, schools and hospitals, youth and senior services, disability programs, environmental and wildlife protection, and other community-based efforts. IRS-qualified organizations with global health-related programming that fits these areas may be eligible.
Max and Victoria Dreyfus Foundation
Ameriprise Financial Support for Community Vitality
Applications due Jan 15, 2027
Nonprofit 501(c)(3) organizations working on basic needs, community development, or cultural enrichment in South Dakota and across the U.S. may be eligible for Ameriprise Financial Community Grants. Focus areas include hunger relief, shelter and supportive housing, adult self-sufficiency, neighborhood revitalization, arts education, and access to cultural programs, especially where Ameriprise volunteers are engaged.
Ameriprise Financial
Dr Scholl Foundation Grants for Global Programs
Letter of inquiry due Jan 31, 2027
Nonprofit 501(c)(3) organizations can seek project funding in areas like health care, education, social services, and environmental initiatives, including work connected to global health in South Dakota. Grants from Dr Scholl Foundation help U.S. and select international organizations with one-year projects, offering US $5,000 - US $25,000 through an annual October–March cycle.
Dr Scholl Foundation
O'Reilly Automotive Foundation Grants for South Dakota Health
Applications due Apr 15, 2027
Nonprofit 501(c)(3) organizations improving health, economic stability, or disaster relief services in South Dakota communities can seek project, general operating, or capital support. Grants from O'Reilly Automotive Foundation help U.S.-based community-focused charities address global health-related needs like access to care, mental health, sanitation, hunger, homelessness, and workforce readiness where O’Reilly Auto Parts operates.
O'Reilly Automotive Foundation Inc
Chick Fil A Foundation Grants for Community Programs
Applications due May 1, 2027
South Dakota nonprofits and 501(c)(3)-equivalent charities working on youth education, family services, food security, or environmental stewardship can access funding through Chick Fil A Foundation’s True Inspiration Awards. Grants of US $30,000 - US $350,000 support programs caring for people, addressing hunger, strengthening communities, and caring for the planet, which may include global health-related initiatives.
Chick Fil A Foundation Inc
Collaborative Community Partnership Grants from Mutual of America
Applications due Jul 1, 2027
Nonprofit organizations in South Dakota with strong, replicable community partnerships can apply for Mutual of America Foundation’s national Community Partnership Award to recognize and support collaborative solutions to significant social issues. U.S. nonprofits working in areas such as global health may be eligible if they demonstrate exemplary, impact-driven partnerships across sectors.
Mutual Of America Foundation