Iowa Community Development Funding via US Bank Foundation
Iowa 501(c)(3) nonprofits working on economic and workforce advancement, safe and affordable housing, or community arts and culture can access funding through US Bancorp Foundation’s Community Possible program. Organizations serving designated U.S. Bank communities, advancing diversity, equity, and inclusion, and addressing multiple pillars may be especially competitive, including programs that support people affected by addiction or substance use disorders.
US Bancorp Foundation
Costco Foundation Grants for Iowa Youth Services
Nonprofit 501(c)(3) organizations in Iowa supporting children, education, and health and human services may be eligible for monetary program support. Grants from Costco Foundation help youth- and family-serving programs demonstrate measurable outcomes, address documented community needs, and show broad financial backing. Addiction and substance use organizations with qualifying child- or education-focused services may fit these priorities.
Costco Foundation
Innovative Human Services Funding from Creag Foundation
Iowa 501(c)(3) nonprofits with innovative human services or social problem-solving programs can access funding through Creag Foundation to develop or expand new approaches. Organizations addressing addiction and substance use disorders as part of broader human services may be eligible, but must have held 501(c)(3) status for at least one year and typically begin with a letter of inquiry.
Creag Foundation
Youth and Child Welfare Grants from DanPaul Foundation
With a mission to support youth health, education, and welfare, 501(c)(3) nonprofits in Iowa and beyond can seek up to US $15,000 for programs serving children and young people. The DanPaul Foundation funds initiatives such as child advocacy, homelessness and poverty services, refugee enrichment, and youth development, which may benefit addiction and substance use prevention efforts.
The Dan Paul Foundation
Draper Richards Kaplan Social Impact Grants in Iowa
Early-stage, independent nonprofit and impact-first for-profit organizations tackling urgent social or environmental problems in Iowa can apply for up to US $300,000 from Draper Richards Kaplan Foundation. Focused on scalable, systems-based solutions for underserved communities, organizations working on addiction, substance use, or related health and poverty issues may be competitive candidates.
Draper Richards Kaplan Foundation
Tech-Enabled Social Impact Funding from Cisco
Nonprofit and nongovernmental organizations using technology to tackle major social challenges in Iowa and worldwide can seek Global Impact Cash Grants, with awards up to US $100,000 for innovative programs. Cisco Systems Foundation supports crisis response, education access, and economic empowerment for predominantly economically underserved communities, which may include addiction and recovery-related services within these areas.
Cisco Systems Foundation
State Farm Community Safety Grants in Iowa
Educational institutions, government programs, 501(c)(3) nonprofits, and 501(c)(4) volunteer fire companies in Iowa can seek funding for safety, education, and community development initiatives. Grants from State Farm Companies Foundation help support auto and home safety, disaster preparedness and recovery, affordable housing, job training, financial literacy, and K-12 and higher education programs, which may benefit addiction and substance use recovery efforts.
State Farm Companies Foundation
Hearst Foundation Support for Cultural Programs
U.S.-based 501(c)(3) cultural institutions with audited expenses over $2 million can seek funding for arts and science programs that engage youth and demonstrate lasting impact, including organizations in Iowa. William Randolph Hearst Foundation supports program, capital, and limited general or endowment needs for museums, performing arts groups, arts schools, and similar nonprofits.
William Randolph Hearst Foundation
Health and Community Funding from Labcorp Charitable Foundation
Nonprofit and charitable-equivalent organizations working on health, education, or community programs in Iowa can use these grants to support food pantries, healthcare access, STEM education, or healthy lifestyle initiatives. Grants from Labcorp Charitable Foundation help U.S.-based groups that may include addiction and substance use services as part of broader health and welfare efforts.
Labcorp Charitable Foundation
Iowa Youth Opportunity Funding via Michael & Susan Dell Foundation
Nonprofits, social enterprises, schools, governments, and other eligible organizations in Iowa working on education or children’s health can apply for more than US $50,000 from the Michael & Susan Dell Foundation for project support or scaling. Programs serving urban low-income children and families, including those addressing addiction-related risks or impacts, may be competitive.
Michael & Susan Dell Foundation
Roche Philanthropy Community Grants in Iowa
Nonprofit charities in Iowa seeking support for humanitarian, social, science education, community, environmental, or contemporary arts projects can apply for philanthropic funding; awards are managed locally by Roche affiliate offices. With a mission to strengthen communities, Roche provides Iowa organizations with support for innovative, sustainable programs that actively engage Roche expertise and employees.
La Roche, Inc.
Health and Human Services Grants from Semnani
Nonprofits providing health, education, or humanitarian services to marginalized communities, including those in Iowa, can apply for Semnani Family Foundation support to expand care and social services. Funding may benefit programs such as healthcare access, child welfare, domestic violence services, literacy, or related human and social services within the U.S. or internationally.
Semnani Family Foundation
Bank of America Support for Community Programs
Nonprofit 501(c)(3) organizations in Iowa can seek sponsorship support for community programs that advance economic mobility and social progress. Focused on housing, jobs, hunger, and community development, Bank of America Charitable Foundation also considers arts, environment, and diversity initiatives, which may benefit addiction and substance use recovery efforts in local communities.
Bank Of America Charitable Foundation Inc
Gupta Family Foundation Support for Human Services
Applications due Jul 31, 2026
Non-sectarian human and social service nonprofits addressing disadvantage and self-reliance, including addiction or substance use challenges, can seek US $5,000 - US $250,000 in funding, including in Iowa. Gupta Family Foundation supports smaller, founder-led organizations, typically 501(c)(3)s or qualifying foreign entities, currently active in the U.S. and select countries worldwide.
Gupta Family Foundation
Hansen Family Foundation Support for Community Programs
Applications due Sep 11, 2026
Nonprofit 501(c)(3) organizations in Iowa seeking support for children, education, humanitarian, environmental, animal, or arts and culture programs can apply for grants of US $1,000 - US $10,000. Focused on life, liberty, and the pursuit of happiness, Hansen Family Foundation may support addiction-related services that fit within these priorities and size limits.
Hansen Family Foundation
Jesse W Couch Foundation Grants for Storytelling
Applications due Sep 25, 2026
Nonprofit 501(c)(3) organizations and aligned for-profits can seek more than US $50,000 to create storytelling projects that highlight their impact in communities, including Iowa. Grants from Jesse W Couch Charitable Foundation help organizations in preservation, education, or wellness share their work, which may include mental health or wellness programs connected to addiction and substance use recovery.
Jesse W Couch Charitable Foundation
Humanitarian and Relief Funding for Nonprofits from Robinson Foundation
Applications due Oct 15, 2026
Focused on humanitarian relief and community support, Robinson Foundation invites Southern-region 501(c)(3) organizations to apply for single-year project funding. Eligible nonprofits must be at least three years old and work in areas like disaster relief, poverty relief, health, families, or veterans’ services, which may benefit addiction and substance use programs in Iowa’s neighboring Southern states.
Robinson Foundation
Community and Environment Grants for Nonprofits from Dudley T Dougherty Foundation
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding may be eligible for funding, including those serving Iowa. Grants from Dudley T Dougherty Foundation help support broad, charitable initiatives that respect people, the environment, and quality of life, which can include programs connected to addiction and substance use recovery.
Dudley T Dougherty Foundation Inc
Georgia-Pacific Foundation Grants for Iowa Communities
Applications due Oct 31, 2026
Nonprofit 501(c)(3) organizations, public schools, and qualified local government entities supporting education, entrepreneurship, environment, or community enrichment in Iowa communities near Georgia-Pacific facilities can apply for funding. Georgia-Pacific Foundation provides grants to programs that enhance long-term well-being and sustainability within 30 miles of its manufacturing communities, which may include addiction and substance use initiatives.
Georgia-Pacific Foundation
Iowa Youth and Basic Needs Funding via TJX Foundation
Letter of inquiry due Oct 31, 2026
With a mission to help vulnerable families and children build better futures, TJX Foundation provides Iowa nonprofits with support for basic needs, youth enrichment, workforce readiness, and safety from domestic violence. Eligible 501(c)(3) organizations within 15 miles of a TJX location may benefit, including those whose addiction-related work intersects these priority areas.
The Tjx Foundation Inc
Max and Victoria Dreyfus Support for Iowa Nonprofits
Applications due Nov 11, 2026
Focused on community-based programs, the Max and Victoria Dreyfus Foundation invites Iowa nonprofit organizations to request US $1,000 - US $20,000 for projects where modest funding can have a big impact. Eligible U.S.-based 501(c)(3)s, including those offering prevention, treatment, or recovery services for addiction and substance use, may benefit from this opportunity.
Max and Victoria Dreyfus Foundation
Dr Scholl Foundation Grants for Iowa Nonprofits
Letter of inquiry due Jan 31, 2027
With a mission to support innovative, practical solutions, Dr Scholl Foundation provides Iowa 501(c)(3) organizations with funding for education, social services, health care, civic and cultural, and environmental projects. U.S.-based nonprofits addressing addiction or substance use within these broad areas may be eligible for one-year grants of US $5,000 - US $25,000.
Dr Scholl Foundation
O'Reilly Automotive Foundation Community Grants in Iowa
Applications due Apr 15, 2027
U.S.-based 501(c)(3) nonprofits serving Iowa communities with programs in economic stability, workforce development, health and social services, or disaster relief can apply for funding from O'Reilly Automotive Foundation. Eligible organizations may receive project, general operating, or capital support, which can include addiction, mental health, or related services for underserved individuals and families.
O'Reilly Automotive Foundation Inc
Community Programs Funding from Union Pacific Foundation
Applications due Apr 30, 2027
Iowa 501(c)(3) nonprofits and independent emergency response organizations can seek US $5,000 - US $30,000 for safety, workforce development, community vitality, or environmental sustainability projects that primarily serve a Union Pacific community. Addiction and substance use programs that fit these priorities, especially those addressing community safety or basic needs, may be eligible.
Union Pacific Foundation
Iowa Youth and Community Funding via Chick Fil A Foundation
Applications due May 1, 2027
Nonprofit 501(c)(3) organizations in Iowa working with youth, families, education, housing, food insecurity, or environmental stewardship can seek US $30,000 - US $350,000 through Chick Fil A Foundation’s True Inspiration Awards. Programs serving underserved young people, including those affected by addiction or substance use, may be competitive across its Caring for People, Food, Community, and Planet categories.
Chick Fil A Foundation Inc
Community Partnership Funding from Mutual of America Foundation
Applications due Jul 1, 2027
Nonprofit organizations across the U.S. that lead strong cross-sector partnerships to tackle significant social issues can receive national recognition and support through the Community Partnership Award, open to Iowa groups as well. Mutual of America Foundation honors six exemplary partnerships annually, highlighting models that improve communities and can be replicated or scaled.
Mutual Of America Foundation
Southwest Iowa Addiction Funding via Community Foundation
Applications due Jul 15, 2027
Nonprofit service providers addressing mental health and substance abuse in southwest Iowa can apply for Community Foundation for Western Iowa’s Southwest Iowa Mental Health and Substance Use Fund, with awards of US $500 - US $2,500 for education, awareness, and provider training. Eligible organizations serve Cass, Fremont, Harrison, Mills, Monona, Montgomery, Page, Pottawattamie, or Shelby counties.
Community Foundation For Western Ia