Science Education Funding from Amgen Foundation
Puerto Rico nonprofits and public institutions focused on science education and community programs can access funding through Amgen Foundation for scalable, replicable initiatives. Eligible 501(c)(3) charities and U.S. governmental organizations may apply, with priority for hands-on STEM learning, teacher professional development, pivotal science experiences, and civic engagement in Juncos and other Amgen communities.
The Amgen Foundation Inc
Auto Club Group Foundation Support for Safety
Puerto Rico nonprofits, schools, governments, and first responder agencies can access funding for traffic safety, driver education, and K–12 financial literacy programs through the Auto Club Group Foundation; awards US $5,000 - US $15,000. Eligible organizations across the foundation’s 14-state and 2-territory footprint may also apply for passive speed enforcement equipment like speed display signs.
The Auto Club Group Foundation
Creag Foundation Support for Puerto Rico Innovators
Nonprofit 501(c)(3) organizations with innovative human services or social problem-solving programs in Puerto Rico may be eligible for funding to develop or expand their work. Grants from Creag Foundation help smaller or evolving organizations test new approaches to existing or previously unaddressed social issues through invited proposals following a letter of inquiry.
Creag Foundation
Tech-Enabled Social Impact Funding from Cisco
Nonprofits and NGOs using technology to address crisis response, education access, or economic empowerment in Puerto Rico can apply for Cisco Systems Foundation’s Global Impact Cash Grants, with awards up to US $100,000. Eligible programs must primarily serve economically underserved communities and present innovative, early-stage solutions rather than sustaining existing efforts.
Cisco Systems Foundation
Community Safety and Education Grants from State Farm
Educational institutions, government programs, 501(c)(3) nonprofits, and 501(c)(4) volunteer fire companies in Puerto Rico can seek Good Neighbor Citizenship funding for safety, education, and community development initiatives. State Farm Companies Foundation supports projects like disaster preparedness, affordable housing, financial literacy, workforce training, and K–12 or higher education that create long-term, sustainable community impact across the U.S.
State Farm Companies Foundation
Hearst Foundation Culture Grants in Puerto Rico
Nonprofit cultural institutions in Puerto Rico offering arts or science programming for broad audiences can seek more than US $100,000 to support programs, capital needs, or limited general operations. With a mission to strengthen cultural access, William Randolph Hearst Foundation prioritizes arts education, artist development, and STEAM-focused initiatives that demonstrate measurable, lasting impact.
William Randolph Hearst Foundation
Puerto Rico Social Service Funding via Hearst Foundation
Nonprofit organizations in Puerto Rico working on social services like poverty alleviation, housing, food access, workforce readiness, or youth development can seek more than US $100,000 to support proven, scalable programs. With a mission to help people build healthy, productive lives, William Randolph Hearst Foundation provides program, capital, and general support to large, U.S.-based 501(c)(3) organizations.
William Randolph Hearst Foundation
Puerto Rico Community Health Funding via Labcorp
Nonprofit organizations focused on health, education, or community services in Puerto Rico can seek support for programs such as food pantries, healthcare for underserved populations, STEM education, and preventative health initiatives. Focused on equitable care and education, Labcorp Charitable Foundation invites eligible 501(c)(3) organizations to apply during its March and September review cycles.
Labcorp Charitable Foundation
Michael & Susan Dell Foundation Support for Education
Nonprofits and social enterprises working on education, health, or family economic stability projects in Puerto Rico may be eligible for grants of more than US $50,000 to support or scale their work. Grants from Michael & Susan Dell Foundation focus on urban low-income children and youth in the U.S., India, and South Africa.
Michael & Susan Dell Foundation
Global Health and Relief Funding from Semnani
Nonprofit organizations providing health, education, or disaster relief services to marginalized communities can apply for grants that support medical care, social services, literacy, and humanitarian aid. Grants from Semnani Family Foundation help Puerto Rico nonprofits and other groups worldwide expand programs for vulnerable children, women, and families, including healthcare access, disease prevention, and emergency response.
Semnani Family Foundation
Sidney Stern Memorial Trust Support for Nonprofits
U.S.-based 501(c)(3) organizations conducting charitable, scientific, medical, or educational work can apply for the Sidney Stern Memorial Trust; awards support projects carried out within the U.S. Puerto Rico nonprofits that meet IRS and, when applicable, California tax-exempt requirements may be eligible if their funded activities occur in the U.S.
Sidney Stern Memorial Trust
Bank Of America Foundation Community Grants in Puerto Rico
Nonprofit 501(c)(3) organizations in Puerto Rico can seek sponsorship support for community-focused programs, including housing, jobs, hunger, arts, and cultural initiatives. Focused on strengthening communities, Bank Of America Charitable Foundation invites nonprofits to propose projects that preserve neighborhoods, develop the workforce, address basic needs, and promote diversity, inclusion, and environmental stewardship.
Bank Of America Charitable Foundation Inc
Human Services Funding from Gupta Family Foundation
Applications due Jul 31, 2026
Nonprofit organizations helping disadvantaged people become self-reliant can apply for Gupta Family Foundation grants supporting human and social services, poverty alleviation, disability services, and disaster relief. The foundation awards US $5,000 - US $250,000 to smaller organizations worldwide, which may include Puerto Rico-based 501(c)(3)s meeting its mission, size, and non-sectarian criteria.
Gupta Family Foundation
Hansen Family Foundation Community Impact Grants
Applications due Sep 11, 2026
Nonprofit 501(c)(3) organizations in Puerto Rico working on children’s services, education, humanitarian aid, animals, environment, or arts and culture can apply for Hansen Family Foundation grants, with awards of US $1,000 - US $10,000. Eligible U.S.-based nonprofits worldwide may benefit if they align with the foundation’s mission and size requirements.
Hansen Family Foundation
Puerto Rico Storytelling Funding via Jesse W Couch Charitable Foundation
Applications due Sep 25, 2026
Puerto Rico nonprofits focused on wildlife conservation, preservation, education, or wellness can access funding through the Jesse W Couch Charitable Foundation’s Storytelling Grant to share their community impact. Eligible 501(c)(3) and aligned for-profit organizations may receive more than US $50,000 to develop storytelling projects that highlight their transformational work.
Jesse W Couch Charitable Foundation
Youth and Family Services Funding from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations supporting basic needs, at-risk youth, or domestic violence services near TJX locations, including Puerto Rico, can seek program funding through The TJX Foundation. With a mission to help vulnerable families and children build better futures, TJX Foundation provides invitation-only grants following an eligibility questionnaire and Letter of Inquiry process.
The Tjx Foundation Inc
Lawrence Foundation Grants for Puerto Rico Nonprofits
Applications due Nov 1, 2026
Nonprofit 501(c)(3) organizations, public schools, and libraries in Puerto Rico can apply for Lawrence Foundation grants of US $5,000 - US $10,000 to support environmental, human services, disaster relief, and other programs. Funding is available for general operating or project expenses, issued as unrestricted support, with no geographic restrictions and reasonable indirect costs allowed.
Lawrence Foundation
US $100,000 - US $500,000
Veteran Housing Funding from Thdf II
Applications due Dec 12, 2026
Puerto Rico 501(c)(3) nonprofits developing multifamily permanent supportive housing for low-income veterans can access funding through Thdf II for new construction or rehabilitation hard costs. Grants of US $100,000 - US $500,000 are available to experienced veteran-housing providers with strong co-funding, long-term veteran occupancy commitments, and integrated supportive services.
Thdf Ii Inc
US $200,000 - US $22,000,000
Office of Population Affairs Health Grants in Puerto Rico
Applications due Jan 11, 2027
Nonprofit and public entities providing family planning and reproductive health services in Puerto Rico can apply for US $200,000 - US $22,000,000 to deliver comprehensive Title X family planning projects. With a mission to expand access to voluntary family planning, the Office of Population Affairs provides multi-year support for education, counseling, and related clinical services for low-income and uninsured individuals.
US Dept. of Health & Human Services: Office of Population Affairs
Ameriprise Financial Support for Community Vitality
Applications due Jan 15, 2027
Nonprofit 501(c)(3) organizations working on basic needs, community development, or volunteer-driven causes in Puerto Rico may be eligible for Ameriprise Community Grants. Grants from Ameriprise Financial help U.S.-based nonprofits address hunger, shelter, adult self-sufficiency, cultural enrichment, and neighborhood economic vitality, with priority given where Ameriprise employees and advisors actively volunteer.
Ameriprise Financial
Preservation Grants for Nonprofits from CLIR
Applications due Feb 24, 2027
U.S. nonprofit academic, research, cultural heritage institutions, government cultural units, and tribal entities can apply for Council on Library and Information Resources grants of US $10,000 - US $50,000 to digitally reformat at-risk audio and audiovisual collections. Puerto Rico organizations preserving rare recordings and historical archives may be especially well positioned for this national program.
Council on Library and Information Resources (CLIR)
Film Preservation Funding from National Film Preservation Foundation
Letter of inquiry due Mar 20, 2027
Public and 501(c)(3) nonprofit archives, libraries, museums, universities, and historical societies in Puerto Rico can seek funding to preserve culturally and historically significant American orphan films. Focused on film preservation, the National Film Preservation Foundation offers US $1,000 - US $20,000 for new lab work creating preservation elements, film prints, and public access copies.
National Film Preservation Foundation
Film Preservation Grants for Nonprofits from National Film Preservation Foundation
Letter of inquiry due Mar 20, 2027
Nonprofit and public film archives with prior NFPF grant experience can apply for US $20,001 - US $75,000 to preserve, reconstruct, or restore significant American orphan films. Grants from National Film Preservation Foundation help institutions in Puerto Rico and across the U.S. fund laboratory work and create new preservation and public access copies.
National Film Preservation Foundation
O'Reilly Automotive Foundation Support for Community Services
Applications due Apr 15, 2027
Nonprofit 501(c)(3) organizations in Puerto Rico providing community-benefit programs may be eligible for project, operating, or capital support that improves quality of life for underserved people. With a mission to strengthen communities, O'Reilly Automotive Foundation provides funding for economic stability, workforce development, health and social services, and disaster relief in areas where O’Reilly Auto Parts operates.
O'Reilly Automotive Foundation Inc
Avant-Garde Film Preservation Funding from National Film Preservation Foundation
Pre proposal due May 8, 2027
Nonprofit and public film archives in the U.S., including those in Puerto Rico, can seek $5,000 to $50,000 to preserve significant American avant-garde films. Grants from the National Film Preservation Foundation fund new laboratory work to create preservation elements and public access copies for historically important experimental works made over twenty years ago.
National Film Preservation Foundation
Housing Innovation Funding from Enterprise Community Partners
Applications due May 16, 2027
Nonprofits, mission-oriented for-profits, and eligible housing entities in Puerto Rico and across the U.S. can seek support for scalable affordable housing innovations through the National Housing Innovation Grant competition. Enterprise Community Partners and Wells Fargo will award US $2,000,000 grants for proven solutions in housing design and construction, finance, or service delivery and programs.
Enterprise Community Partners Inc
Community Partnership Funding from Mutual of America Foundation
Applications due Jul 1, 2027
Nonprofit organizations with exemplary community partnerships can receive national recognition and funding support for collaborative social impact work, including those in Puerto Rico. Mutual of America Foundation’s Community Partnership Award honors U.S. nonprofits that jointly address significant social issues with public, private, or social sector partners and demonstrate models that can be replicated in other communities.
Mutual Of America Foundation