Best Large Grants for Nonprofit Organizations in Puerto Rico

McCormick & Company, Inc. actively supports charitable contributions through its Charitable Donations Committee (CDC), which prioritizes donations to non-profit organizations that enhance education, health, environment, and culture. The CDC focuses on organizations that benefit communities where McCormick employees live and work, ensuring a positive impact. Eligible groups must be tax-exempt and demonstrate a commitment to non-discrimination. However, donations are not made to individuals, political organizations, or entities that conflict with corporate values.

The Creag Foundation, established in 2009 in Woodinville, Washington, provides funding to innovative 501(c)(3) nonprofit organizations addressing social issues. Focused on smaller organizations, the foundation seeks to support those with unique approaches to improve the human condition. Eligible applicants must have held 501(c)(3) status for at least one year and present a new or previously unaddressed solution to societal challenges. Applications are by invitation only, encouraging creativity and passion in charitable work.

Early-stage nonprofit and impact-driven for-profit organizations tackling major social or environmental challenges can access up to US $300,000 from Draper Richards Kaplan Foundation to scale proven solutions. Grants from Draper Richards Kaplan Foundation help Puerto Rico and global social impact ventures grow capacity, refine models, and expand reach to underserved communities.

Nonprofit organizations in Puerto Rico tackling chronic poverty and related social and economic challenges can apply for more than US $100,000 to support program, capital, or general operations. With a mission to strengthen social services, William Randolph Hearst Foundation prioritizes scalable efforts in areas like affordable housing, food access, job training, legal aid, reentry, and youth development.

Puerto Rico 501(c)(3) nonprofits focused on health, education, or community services can seek funding for programs like food pantries, healthcare access for underserved populations, STEM education, and preventive health initiatives. Focused on community well-being, Labcorp Charitable Foundation invites eligible organizations to apply during its March and September review cycles.

Nonprofits and social enterprises working on education, children’s health, or family economic stability projects can access funding of more than US $50,000 for project support or scaling in Puerto Rico and other eligible locations. Grants from Michael & Susan Dell Foundation prioritize initiatives serving urban low-income children and youth in the U.S., India, and South Africa.

Nonprofit organizations running humanitarian, social, education, or community programs in Puerto Rico or serving U.S. communities can seek charitable donations and sponsorships to support their initiatives. Amgen Foundation provides funding to eligible 501(c)(3) public charities, qualified Puerto Rico charities, and U.S.-based governmental entities for charitable and educational purposes.

Puerto Rico nonprofit organizations and public schools serving children and youth through education, healthcare, or human services programs can access funding through Oriental Trading Company. Eligible applicants must be 501(c)(3) organizations or public educational institutions focused on improving the lives, health, and academic success of children and youth, which may benefit local large-scale initiatives.

Accredited charities in Puerto Rico working on humanitarian, education, community, environmental, or contemporary arts projects can apply for Roche’s corporate donations program to support high-quality, sustainable initiatives. Projects should allow use of Roche expertise, engage local affiliates and employees, and be managed locally within Puerto Rico through the relevant Roche office.

Nonprofit organizations providing health, education, or humanitarian services to marginalized communities can apply for grants that support healthcare access, disaster relief, and social services. Grants from Semnani Family Foundation help Puerto Rico nonprofits and other international organizations deliver medical care, child and women’s health programs, literacy initiatives, and emergency relief where needs are greatest.

U.S.-based 501(c)(3) organizations conducting charitable, scientific, medical, or educational work can apply for the Sidney Stern Memorial Trust’s national funding; awards support projects carried out within the U.S. Puerto Rico nonprofits that meet these criteria and operate qualifying programs may be eligible for this broadly focused support.

Nonprofits, NGOs, and institutions with annual budgets of at least $2M in Puerto Rico can apply for TED’s Audacious Project to scale bold, proven solutions to urgent global challenges. Eligible changemakers may receive multi-year philanthropic support, strategic idea shaping, and visibility for initiatives in areas like health, climate, social justice, and education.

The Bank of America Foundation Sponsorship Program aims to enhance economic mobility and social progress in low- and moderate-income communities through partnerships with nonprofit organizations. This initiative focuses on critical areas such as workforce education, basic needs like food and housing, and community development. The Foundation invested $350 million last year and encourages employee volunteerism and giving, supporting nonprofits in various sectors, including arts, culture, and diversity initiatives.

The Zegar Family Foundation Grant, established in 2007, focuses on improving lives through impactful charitable donations. The foundation prioritizes areas such as environment, justice, human rights, science, education, and community development. While unsolicited proposals are not accepted, the foundation remains open to innovative ideas that align with its mission. Through targeted support, it aims to create lasting positive change in communities and promote social equity.

The Journey For Good Grant aims to combat poverty by supporting charitable organizations in North America focused on food security, housing, education, and workforce development. The grant prioritizes initiatives that provide nutritional wellness, combat homelessness, and support veterans and their families. By fostering partnerships among nonprofits, government, and business, the foundation addresses the interconnected challenges faced by economically vulnerable individuals, creating sustainable solutions for community empowerment.

Puerto Rico 501(c)(3) nonprofits and aligned for-profit organizations can access funding to tell impactful stories about their work through the Storytelling Grant, which supports projects across preservation, education, and wellness. Large grants of more than US $50,000 from Jesse W Couch Charitable Foundation may benefit wildlife conservation and related initiatives.

Southern U.S. 501(c)(3) public charities with at least three years of activity can seek single-year program funding for humanitarian, family, education, health, and related services from the Robinson Foundation. Organizations in Puerto Rico working in areas like poverty relief, disaster response, children and families, or medical assistance may be eligible if they meet the regional and mission criteria.

Nonprofit 501(c)(3) organizations working on community services, environmental conservation, or peacebuilding may be eligible for funding that can support programs in Puerto Rico and beyond. Focused on broad social and environmental impact, the Dudley T Dougherty Foundation invites charitable organizations to propose projects that advance respect for people, life, and the environment.

Nonprofit 501(c)(3) organizations near TJX locations that support basic needs, at-risk youth, or domestic violence services in Puerto Rico and beyond can seek grants for program support. With a mission to help vulnerable families and children build better futures, TJX Foundation provides funding for basic needs, education and training, patient care, and empowering women.

Puerto Rico 501(c)(3) nonprofits developing multifamily permanent supportive housing for low-income veterans can access funding through THDF for new construction or rehabilitation hard costs. Grants of US $100,000 - US $500,000 support projects where at least 20% of units are reserved for veterans and long-term veteran occupancy is contractually ensured.

Nonprofit 501(c)(3) organizations working on basic needs, community development, cultural enrichment, or volunteer-driven causes in Puerto Rico may be eligible for Ameriprise Community Grants. Grants from Ameriprise Financial help U.S.-based nonprofits address hunger, shelter, adult self-sufficiency, neighborhood revitalization, arts access, and other programs that show measurable results and engage Ameriprise volunteers.

The Robert F. Schumann Foundation Grant supports organizations dedicated to environmental sustainability, education, and the arts. Founded by Robert F. Schumann, an environmentalist, the foundation aims to enhance the quality of life for both humans and animals. It prioritizes projects that would not have been pursued without its assistance, particularly in ornithology and open space habitats. Organizations must be 501(c)(3) exempt to apply, ensuring a focus on impactful community initiatives.

Nonprofit 501(c)(3) organizations in Puerto Rico working on youth education, food security, housing, or environmental stewardship can receive US $30,000 - US $350,000 in program support. Chick Fil A Foundation’s True Inspiration Awards back initiatives for underserved youth and their families, including leadership development, hunger relief, family services, and community or environmental projects.

Consultants and evaluation firms in Puerto Rico can apply for Enterprise Community Partners’ RFP to provide program evaluation and related services, including quantitative and qualitative analysis, training, and reporting support. Those with experience in equitable and affordable housing, community development, or data systems may be especially competitive for this national, as-needed contract opportunity.

Nonprofit organizations with exemplary community partnerships can seek national recognition and support for collaborative social impact work in Puerto Rico and across the U.S. Mutual of America Foundation provides its Community Partnership Award to six nonprofits annually, honoring innovative, replicable partnerships that measurably improve lives and address significant social issues through cross-sector collaboration.

The Gupta Family Foundation Grant aims to empower disadvantaged individuals by providing financial support to organizations that foster self-reliance. Headquartered in Herndon, Virginia, the foundation offers grants ranging from $5,000 to over $250,000, prioritizing smaller organizations with a strong commitment to their missions. Eligibility typically includes US-based IRS 501(c)(3) entities, with operations extending to countries like India and Kenya. The foundation emphasizes mission alignment and effective resource allocation to ensure maximum impact.

T7 Social Impact GrantsThe T.D. Jakes Foundation (TDJF), in partnership with Wells Fargo, is proud to launch the Social Impact Grant Challenge, a transformative funding opportunity designed to identify, support, and amplify nonprofit organizations creating meaningful change in communities across the United States.

Designed around the T.D. Jakes Foundation's pillars of service (Educational Access & Workforce Readiness, financial inclusion, and community transformation and well-being), the Challenge seeks innovative nonprofit organizations that are addressing critical social issues through impactful, scalable, and sustainable solutions.

Finalists selected through this process will have the opportunity to showcase their organization through a live presentation at the inaugural Thriving Seven (T7) Summit, taking place November 12 –14 in Atlanta, Georgia. In addition to competing for grant funding, finalists will gain national visibility for their work and connect with nonprofit leaders, funders, and changemakers from across the country.Grant Funding: A total of $1,500,000 in grant funding is anticipated to be awarded: 

• One (1) - $500,000 grant
• One (1) - $250,000 grant
• Two (2) - $100,000 grant
• Eleven (11) - $50,000 grant