South Carolina Infrastructure Funding via Appalachian Regional Commission
State and local agencies, local governing boards, nonprofits, tribes, and higher education institutions in eligible Appalachian South Carolina counties can apply for Appalachian Regional Commission’s Area Development grants to support critical infrastructure and workforce and business development projects. Funding may benefit community development efforts focused on water and wastewater systems, transportation, broadband, entrepreneurship, and worker training.
Appalachian Regional Commission
Community Impact Grants for Nonprofits from Triangle Community Foundation
South Carolina community development nonprofits can access funding through Triangle Community Foundation’s Clancy & Theys 1949 Fund to support measurable, lasting community impact. Grants up to US $10,000 prioritize education and workforce development, youth programming and enrichment, and community well-being, including access to healthcare, housing, and essential social services in regions where Clancy & Theys operates.
Triangle Community Foundation
South Carolina Community Development Funding via Duke Energy Foundation
Nonprofit 501(c)(3) organizations and government entities in South Carolina communities served by Duke Energy can access funding through the Duke Energy Foundation for community development, workforce training, and climate resiliency projects, with awards up to US $20,000. Eligible projects include economic revitalization, disaster preparedness, STEM education, and opportunity and inclusion initiatives in local communities.
The Duke Energy Foundation
South Arts Grants for South Carolina Arts
With a mission to advance Southern vitality through the arts, South Arts provides South Carolina arts nonprofits and public arts agencies with up to US $1,000 for professional development. Funding supports staff or board participation in conferences, workshops, and trainings, including travel, registration, and consultant fees, helping smaller arts organizations build capacity and strengthen community programming.
South Arts, Inc.
Grassroots Justice Funding from Southern Partners Fund
South Carolina rural community groups using grassroots organizing for social, economic, or environmental justice can access funding through Southern Partners Fund for community organizing, capacity building, and travel assistance. Eligible groups are self-governed by the rural population they serve and may work on education reform, immigration rights, or voter engagement, with awards up to US $3,500.
Southern Partners Fund
Yawkey Foundation Grants for South Carolina Facilities
Focused on capital projects, Yawkey Foundation invites South Carolina 501(c)(3) nonprofits to seek up to US $5,000,000 to develop or improve physical spaces that enhance direct services. Organizations in Georgetown County working in health care, education, human services, youth athletics, arts and culture, or conservation may be competitive candidates for these transformational capital grants.
Yawkey Foundation
South Carolina Community Systems Change Funding via Sisters of Charity Foundation
Letter of inquiry due Aug 4, 2026
Nonprofit organizations in South Carolina working on systems change for economic mobility or housing security can apply for Sisters of Charity Foundation’s Systems Change Grants, awarding US $15,000 - US $20,000 for one-year projects. Funding may cover general operations, programs, or capacity-building, including advocacy, coalition-building, and other efforts addressing root causes of poverty in local, regional, or state communities.
Sisters of Charity Foundation of South Carolina
Truist Foundation Support for Workforce Development
Applications due Aug 7, 2026
Nonprofit 501(c)(3) organizations providing workforce development and career navigation services for adult workers in South Carolina may be eligible for Truist Foundation’s Inspire Awards, offering US $10,000 - US $250,000. Funding supports training and upskilling, AI readiness and literacy, wraparound services, and career navigation that build economic mobility and stronger local communities.
Truist Foundation Inc
Blue Cross Foundation Support for South Carolina Health
Letter of inquiry due Aug 7, 2026
South Carolina nonprofits, government agencies, and tax-exempt educational or research institutions working to improve health outcomes and access to care can access funding through the Blue Cross and Blue Shield of South Carolina Foundation. Community development efforts that advance oral health, mental health, primary care, or broader public health for economically vulnerable residents may be eligible.
Blue Cross and Blue Shield of South Carolina Foundation
Accessibility Arts Funding from South Arts
Applications due Sep 4, 2026
Nonprofit arts organizations and eligible public or tribal entities in South Carolina can receive US $500 - US $2,500 to make arts programs more accessible for people with disabilities, including audiences and artists. South Arts supports costs like accessibility audits, assistive services, accessible materials, website upgrades, and modest facilities enhancements that improve inclusive community arts participation.
South Arts, Inc.
Dominion Energy Community Grants in South Carolina
Applications due Sep 11, 2026
Grants from Dominion Energy Charitable Foundation help South Carolina 501(c)(3) organizations fund community development, basic human needs, education, environmental stewardship, and related projects. Eligible nonprofits must operate where Dominion Energy provides service or has significant facilities; typical awards range from US $1,000 - US $15,000, with two online cycles each year.
Dominion Energy Charitable Foundation
USDA Rural Development Grants for South Carolina Facilities
Applications due Sep 30, 2026
Public bodies, community-based nonprofits, and federally recognized Tribes in South Carolina rural areas can apply for USDA Rural Development’s Community Facilities funding to develop essential community facilities. Support can cover construction, renovation, equipment, and related costs for projects like health centers, public safety buildings, community centers, and other community development infrastructure in towns under 20,000 residents.
USDA: Rural Development (RD)
American Honda Motor Education Grants in South Carolina
Applications due Nov 1, 2026
South Carolina nonprofits and schools running manufacturing-focused workforce education programs can apply for the Education Pillar Award, offering US $25,000 - US $100,000 for hands-on training initiatives. Focused on future-ready manufacturing roles, American Honda Motor supports programs in areas like design, data analytics, automation, and AI that strengthen local workforce pipelines and community prosperity.
American Honda Motor Co., Inc.
American Honda Motor Grants for South Carolina Environment
Applications due Nov 1, 2026
South Carolina community development and environmental nonprofits, 501(c)(3) fiscal sponsor projects, and eligible schools can access funding for decarbonization, clean energy, and efficient resource use projects. South Carolina organizations can access funding through American Honda Motor for programs like energy-efficiency upgrades, solar or wind installations, recycling, composting, and other sustainability initiatives; awards US $25,000 - US $100,000.
American Honda Motor Co., Inc.
Self Foundation Community Development Grants in South Carolina
Applications due Nov 1, 2026
Nonprofit organizations serving Greenwood, South Carolina, and surrounding counties can apply for Self Foundation’s community development, education, and arts and culture grants. Funding supports programs such as early childhood development, health and wellness, literacy, and historic preservation. Community-based groups working to strengthen local residents’ lives and neighborhoods may be eligible.
Self Foundation
Duke Endowment Grants for South Carolina Child Welfare
Pre proposal due Dec 15, 2026
With a mission to strengthen child and family well-being, the Duke Endowment provides South Carolina child- and family-serving nonprofits with funding to implement and sustain evidence-based programs addressing child abuse and neglect. Accredited agencies with audited financials may secure support for implementation, innovation, and systems-improvement efforts that benefit vulnerable children, youth, and families.
The Duke Endowment
Summer Arts Education Funding for Nonprofits from South Carolina Arts Commission
Applications due Dec 19, 2026
Nonprofit organizations, colleges, universities, and government units in South Carolina can receive support for K-12 summer arts education projects, including camps, workshops, residencies, and public art. The South Carolina Arts Commission offers up to US $15,000 to expand access, address learning loss, and advance standards-based arts instruction that benefits local communities.
South Carolina Arts Commission
Community Foundation of Greenville Support for Community Programs
Letter of inquiry due Jan 15, 2027
Eligible 501(c)(3) organizations or government units in Greenville County, South Carolina can apply for Community Foundation of Greenville’s Greenville Women Giving grants; awards US $50,000 - US $100,000 for high-impact projects. Funding may support arts, education, environment, health, or human services initiatives that strengthen community development and address significant local needs.
Community Foundation of Greenville
The Nature Conservancy Land Protection Grants in South Carolina
Applications due Feb 14, 2027
Nonprofit conservation and community organizations, municipalities, Tribal Nations, and agencies in South Carolina can access funding through The Nature Conservancy’s Resilient and Connected Appalachians Grant Program for fee and easement land acquisition projects. Grants up to US $100,000 support land protection, community engagement, and equitable conservation benefits within the Appalachians Program boundary.
The Nature Conservancy
South Carolina Arts Commission Community Funding
Applications due Feb 28, 2027
Artists, nonprofit organizations, and government units in South Carolina can use this grant to support arts projects, capacity building, and professional development that strengthen local communities. South Carolina Arts Commission supports arts and culture initiatives that may advance community development and revitalization, with awards up to US $2,500 for eligible project costs and equipment.
South Carolina Arts Commission
Community Development Funding from Foundation for the Carolinas
Applications due Mar 27, 2027
South Carolina 501(c)(3) nonprofits, congregations, and governmental or educational institutions can seek project funding for crime and safety, economic development, education, family and youth, and public health initiatives serving Cherokee County residents. Cherokee County Community Foundation, an affiliate of Foundation for the Carolinas, offers these competitive community development grants within South Carolina.
Foundation for the Carolinas
South Carolina Arts Presenter Funding via South Arts
Applications due Apr 22, 2027
Nonprofit and governmental arts presenting organizations in South Carolina can use this grant to fund staff and guest artists’ travel, registration, and related costs for professional development and artistic planning, with awards up to US $1,000. With a mission to strengthen Southern arts presenters, South Arts provides support for film, visual, performing, literary, traditional, and multidisciplinary arts organizations.
South Arts, Inc.
Southern Partners Fund Support for Rural Organizing
Applications due May 6, 2027
Rural, community-based 501(c)(3) organizations using grassroots organizing strategies for social, economic, or environmental justice in South Carolina and other Southeastern states can seek general or project support through the Hubert E. Sapp Regular Grant Cycle. Southern Partners Fund prioritizes small-budget groups building community leadership, strengthening rural communities, and advancing just, community-driven decision-making.
Southern Partners Fund
South Carolina Housing Innovation Funding via Enterprise Community Partners
Applications due May 16, 2027
South Carolina community development and housing organizations with proven, ready-to-scale affordable housing innovations can access funding through Enterprise Community Partners’ National Housing Innovation Grant. This national competition awards US $2,000,000 grants for solutions in design and construction, finance, or service delivery and programs that expand affordable rental and homeownership options.
Enterprise Community Partners Inc
Community Foundation of Greenville Grants for South Carolina Capacity Building
Applications due Jul 17, 2027
South Carolina 501(c)(3) nonprofits operating at least two years and serving Greenville County can access funding through Community Foundation of Greenville for organizational capacity building projects. Grants of US $5,000 - US $12,500 support planning, technology upgrades, management improvements, collaborations, and other efforts that strengthen operations and long-term community impact.
Community Foundation of Greenville
Frances P. Bunnelle Foundation Community Grants
Letter of inquiry due Jul 18, 2027
Eligible 501(c)(3) public charities, houses of worship, government entities, and fiscally sponsored projects in South Carolina’s Georgetown County can apply for Frances P. Bunnelle Foundation’s Grants for the Common Good, awarding US $2,500 - US $15,000 for general operating or special project support. Community development efforts addressing poverty, basic needs, economic vitality, or environmental preservation may be competitive in the fall cycle.
Frances P. Bunnelle Foundation