Costco Foundation Child and Family Grants in South Carolina
Nonprofit organizations supporting children, education, or health and human services in South Carolina can apply for program funding that demonstrates measurable community impact. Grants from Costco Foundation help rural development groups and other 501(c)(3) providers of child welfare, youth services, and related human services in communities where Costco operates. Monetary requests only are considered.
Costco Foundation
Youth Development Funding for Nonprofits from DanPaul Foundation
501(c)(3) nonprofits supporting youth health, education, and welfare can apply for the DanPaul Foundation’s grants, with awards up to US $15,000, including organizations in South Carolina. Funding may support early childhood development, child advocacy, homelessness and poverty services, refugee enrichment, environmental education, and related programs that directly benefit young people.
The Dan Paul Foundation
Community Safety and Development Grants from State Farm
South Carolina rural development organizations and other eligible 501(c)(3)s, educational institutions, government programs, and volunteer fire companies can access funding through State Farm Companies Foundation for safety, education, and community development initiatives. Grants may support projects like disaster preparedness, affordable housing, job training, financial literacy, STEM education, and neighborhood revitalization across rural communities.
State Farm Companies Foundation
William Randolph Hearst Foundation Culture Grants in South Carolina
South Carolina cultural nonprofits with audited expenses over $2 million can access funding through the William Randolph Hearst Foundation for arts and science programs, capital projects, and limited general or endowment support. U.S.-based museums, performing arts organizations, arts schools, and STEAM education programs serving large or underserved populations may be eligible, including those supporting rural development efforts.
William Randolph Hearst Foundation
South Carolina Community Health Funding via Labcorp
South Carolina nonprofits focused on health, education, or community services can access funding through Labcorp Charitable Foundation to expand programs and services. The foundation supports efforts such as food pantries, healthcare for underserved populations, STEM education, and healthy lifestyle initiatives, with requests reviewed twice yearly in March and September.
Labcorp Charitable Foundation
Michael & Susan Dell Foundation Youth Grants in South Africa
Organizations supporting education, health, or family economic stability for children and youth in urban low‑income communities in South Africa can apply for Michael & Susan Dell Foundation grants; awards are More than US $50,000 for project support or scaling. Eligible entities include nonprofits, social enterprises, schools, governments, and other mission‑aligned organizations.
Michael & Susan Dell Foundation
Community Development Funding for Charities from Roche
Focused on community and environmental initiatives, this program invites accredited charities in South Carolina to seek support for humanitarian, social development, science education, and arts projects. Local organizations working on rural development, health, youth services, or disaster relief may be eligible through Roche affiliate offices managing in-country donations and partnerships.
La Roche, Inc.
Health and Human Services Funding from Semnani Family Foundation
Nonprofit and humanitarian organizations working on health, education, and disaster relief for marginalized communities, including those serving rural South Carolina, can seek support for programs improving human welfare. Semnani Family Foundation provides flexible funding for healthcare access, child and women’s health, food security, homelessness, and related social services in the U.S. and internationally.
Semnani Family Foundation
Sidney Stern Memorial Trust Grants for South Carolina Nonprofits
With a mission to support charitable, scientific, medical, and educational work, Sidney Stern Memorial Trust provides South Carolina 501(c)(3) organizations with funding for programs that advance general welfare. Eligible nonprofits must use awarded funds within the U.S., which may include rural development efforts that fit these broad priorities.
Sidney Stern Memorial Trust
Rural Justice Organizing Funding from Southern Partners Fund
Rural community groups in South Carolina working on grassroots organizing for social, economic, or environmental justice can access funding through Southern Partners Fund for small projects, capacity building, and travel. Eligible groups are self-governed by the rural population they serve and may focus on education reform, immigration rights, or voter engagement; awards are up to US $3,500.
Southern Partners Fund
Bank of America Support for Community Development
Nonprofit 501(c)(3) organizations working on community development, basic needs, workforce readiness, arts, environment, or inclusion in South Carolina may be eligible for sponsorship support to strengthen local communities. Bank of America Foundation supports initiatives that preserve neighborhoods, address hunger and shelter, and enhance the economic, social, and cultural life of rural and urban areas across the U.S.
Bank Of America Charitable Foundation Inc
South Carolina Human Services Funding via Gupta Family Foundation
Applications due Jul 31, 2026
Non-sectarian human and social service nonprofits working to help disadvantaged people become self-reliant can apply for Gupta Family Foundation support, with awards from US $5,000 - US $250,000. With a mission to empower disadvantaged individuals, Gupta Family Foundation provides smaller organizations in the U.S., including South Carolina, funding that may benefit rural development efforts.
Gupta Family Foundation
Accessibility Improvements Funding from South Arts
Applications due Sep 4, 2026
Nonprofit 501(c)(3) arts organizations, government units, and tribal communities in South Carolina and other South Arts region states can receive US $500 - US $2,500 to make arts programs more accessible for people with disabilities. South Arts provides support for accessibility programming, staff training, and modest facility enhancements, which may benefit rural development efforts in arts-based communities.
South Arts, Inc.
Storytelling Funding for Nonprofits from Couch Foundation
Applications due Sep 25, 2026
Nonprofit organizations, especially wildlife conservation groups, can seek the Storytelling Grant to share the impact of their preservation, education, or wellness work, including in rural South Carolina communities. Focused on empowering mission-driven storytelling, the Jesse W Couch Charitable Foundation offers awards of more than US $50,000 to highlight real-world change.
Jesse W Couch Charitable Foundation
USDA Rural Development Grants for South Carolina
Applications due Sep 30, 2026
Public bodies, community-based nonprofits, and Federally Recognized Tribes in South Carolina rural areas can apply for USDA Rural Development’s Community Facilities funding to develop essential community facilities. Support can cover purchasing, constructing, or improving facilities and equipment for health care, public safety, community services, education, utilities, and local food systems in eligible small communities.
USDA: Rural Development (RD)
Emergency Water Infrastructure Funding from USDA
Applications due Sep 30, 2026
Eligible rural local governments, nonprofits, and federally recognized tribes in South Carolina can obtain up to US $1,000,000 to construct or repair drinking water sources, intakes, treatment facilities, and transmission lines after emergencies. With a mission to support rural development, USDA Rural Development provides funding to communities facing droughts, floods, disease outbreaks, and other disasters.
USDA: Rural Development (RD)
South Carolina Rural Microenterprise Funding via USDA
Applications due Oct 1, 2026
Rural development and entrepreneurship organizations in South Carolina can receive up to US $500,000 to capitalize rural microloan revolving funds and provide training and technical assistance to microentrepreneurs. Focused on rural development, the United States Department of Agriculture invites eligible Microenterprise Development Organizations to support startup and growth for local microenterprises.
United States Department of Agriculture (USDA)
Youth and Basic Needs Grants from TJX Foundation
Letter of inquiry due Oct 31, 2026
Nonprofit 501(c)(3) organizations near TJX locations in South Carolina can seek funding for basic needs, youth education enrichment, workforce readiness, and safety from domestic violence. The TJX Foundation invites eligible groups that meet its mission and nondiscrimination requirements to complete an eligibility questionnaire, then a letter of inquiry, with full applications by invitation.
The Tjx Foundation Inc
Health Equity Funding for Carolinas Providers via Duke Endowment
Pre proposal due Nov 15, 2026
Not-for-profit hospitals, academic health centers, area health education centers, select organizations in counties without an eligible hospital, and not-for-profit inpatient facilities in South Carolina can seek Health Care grants to improve access and outcomes. The Duke Endowment supports projects for vulnerable rural populations, including maternal and infant health, mental health, oral health, population health, and workforce development.
The Duke Endowment
Summer Arts Education Funding for Nonprofits from South Carolina Arts Commission
Applications due Dec 19, 2026
Nonprofit organizations, colleges, universities, and government units in South Carolina can receive support for summer K-12 arts education projects, including camps, workshops, residencies, and public art. South Carolina Arts Commission provides up to US $15,000 for programs that expand arts access, address learning loss, and may especially benefit rural or high-poverty communities.
South Carolina Arts Commission
Ameriprise Financial Support for Community Vitality
Applications due Jan 15, 2027
Nonprofit 501(c)(3) organizations working on hunger, shelter, adult self-sufficiency, or community vitality programs in the U.S., including South Carolina, may be eligible for Ameriprise Community Grants. Focused on basic needs, economic and cultural development, and volunteer-driven causes, Ameriprise Financial prioritizes measurable outcomes and strong volunteer engagement, which can include rural development initiatives.
Ameriprise Financial
South Carolina Arts Commission Grants for Rural Arts
Applications due Mar 2, 2027
Eligible South Carolina colleges, universities, government units, public libraries, and qualifying nonprofits in rural communities can apply for South Carolina Arts Commission’s Art of Community: Rural SC Grants, awarding up to US $5,000 for arts-based projects. Funding supports rural development through public arts engagement, skill-building, and creative projects across diverse artistic disciplines.
South Carolina Arts Commission
Spartanburg County Foundation Support for Rural Development
Letter of inquiry due Mar 17, 2027
Grants from Spartanburg County Foundation help South Carolina rural development nonprofits and tax-exempt entities strengthen quality of life, educational achievement, and economic mobility for Spartanburg County residents. Eligible 501(c)(3) and tax-exempt organizations may receive up to US $35,000 for programs like health and wellness, adult education, job training, transportation access, and household stability services.
Spartanburg County Foundation
Southern Partners Fund Support for Rural Organizing
Applications due May 6, 2027
Rural, community-based 501(c)(3) organizations using grassroots organizing strategies for social, economic, or environmental justice in South Carolina and other Southeastern states can seek general or project support through this grant cycle. Southern Partners Fund backs small-budget groups building local leadership, strengthening rural communities, and advancing justice-focused campaigns rather than direct services or capital projects.
Southern Partners Fund
South Carolina Housing Innovation Funding via Enterprise Community Partners
Applications due May 16, 2027
South Carolina rural development and housing organizations with proven, ready-to-scale affordable housing innovations can access funding through Enterprise Community Partners and Wells Fargo’s Housing Affordability Breakthrough Challenge. Eligible nonprofits, mission-oriented for-profits, and qualified public or tribal housing entities nationwide compete for US $2,000,000 grants to expand design and construction, finance, or service delivery solutions for affordable homes.
Enterprise Community Partners Inc
US $500,000 - US $3,000,000
Rural Health Care Funding from South Carolina Department of Health and Human Services
Applications due Jun 1, 2027
State and territorial health agencies working on rural health care in South Carolina can access substantial federal support to strengthen rural healthcare systems through this initiative. South Carolina Department of Health and Human Services provides US $500,000 - US $3,000,000 for facility enhancements, workforce investment, and training that bolster rural health infrastructure and resilience.
South Carolina Department of Health and Human Services
USDA Rural Development Support for South Carolina
Applications due Jun 15, 2027
Rural public entities and nonprofit organizations in South Carolina can seek funding to provide technical assistance, training, and infrastructure support for small rural businesses. With a mission to strengthen rural economies, USDA Rural Development provides grants of US $10,000 - US $500,000 for projects like business counseling, facilities, revolving loan funds, incubators, and community or technology-based economic development.
USDA: Rural Development (RD)